2015•Zhongguo xiaoer jijiu yixueRequires access
Th17/Treg cell and pathogenesis of Henoch-Schonlein purpura
Tingting Zhang
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Abstract
Henoch-Schonlein purpura (HSP) is the most common form of childhood autoimmune vascular inflammatory diseases, the incidence rate showed an increasing trend, its pathogenesis has not yet been fully elucidated. Th17 cells are recently discovered to be a new kind of different from Th1, Th2 effector of CD4+ T cell subsets, Th17/Treg imbalance is closely related to the pathogenesis of HSP. The paper reviewed the related researches.
Key words:
Th17 cell; Regulatory T cell; Henoch-Schonlein Purpura; Pathogenesis