Contrast visual acuity and wavefront after implantation of a zero spherical aberration intraocular lens in high myopia

Objective To compare contrast visual acuity and wavefront aberrations in highly myopic eyes implanted with a zero spherical aberration intraocular lens (IOL) and a spherical IOL.Methods A prospective case-controlled study was designed.Twenty-eight high myopia patients were randomized to receive 2 IOL types:Akreos AO (23 eyes),and Rayner SuperflexTM 620H (21 eyes).Complete ophthalmologic examination including best-spectacle corrected visual acuity (BSCVA),Contrast Visual Acuity,and wavefront aberration of the comea and eye were performed 3 months postoperatively. Results The zero spherical aberration IOL group and the spherical IOL group did not differ in baseline characteristics,including age (52.6±5.7 yrs vs 54.1±5.9 yrs,P=0.281),axial length (30.21±2.06mm vs 31.03±2.03mm,P =0.289),Pre-BSCVA (4.68±0.10 vs.4.63±0.12,P =0.248),IOL power (4.88±2.98D vs.3.42±3.83D,P =0.235),Postoperative spherical equivalent refraction (-2.53±1.25D vs.-2.12±0.70D,P =0.273),Post-BSCVA (4.83±0.15 vs.4.76±0.15,P =0.211),and pupil size of 6mm:Postoperative corneal spherical aberration (0.27±0.18μtm vs.0.28±0.16μm,P =0.905),total ocular spherical aberration (0.23±0.14μm vs.0.32±0.16μm,P =0.14),total high-order aberration (1.46±0.48μm vs.1.14±0.50μm,P =0.277),coma aberration (0.68±0.45μm vs.0.73±0.48μm,P =0.782),trefoil aberration (0.55±0.15μtm vs.0.42±0.16μm,P =0.377),under the mesopic condition,100％ Contrast Visual Acuity (0.16±0.19 vs.0.19±0.17,P =0.64),25％ Contrast Visual Acuity (0.39±0.20 vs.0.47±0.22,P =0.31),10％ Contrast Visual Acuity (0.65±0.29 vs.0.78±0.31,P =0.22),5％ Contrast Visual Acuity (0.90±0.24 vs.0.99±0.27,P =0.40). Conclusions The spherical aberration is not considerably lower in the zero spherical aberration IOL group compared with spherical IOL group in high myopia.Under the mesopic condition different Contrast Visual Acuity,the zero spherical aberration IOL does not show better than the spherical IOL. Key words: High myopia;  Intraocular lens;  Aspherical;  Wavefront aberrations;  Contrast Visual Acuity