2007Zhongguo jiceng yiyaoRequires access

Analysis of electric sacral neuromdulation and resiniferatoxin in treatment of primary female overactive bladder

唐华, 廖小七, 饶顺琴, 黄建成, 黄宏, 黄世勇, 陈剑

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Abstract

目的 分析骶神经电刺激与辣椒辣素类似物(RTX)联合治疗女性特发性膀胱过度活动症(IOAB)的疗效.方法 将32例女性IOAB患者采用经皮穿刺电刺激骶3神经及100 nmol/L RTX溶液100ml膀胱灌注治疗3个月,观察治疗前后排尿日记及尿动力学参数,并通过治疗前后抑郁与焦虑的心理评分来分析患者的生活质量有元改善.结果 治疗前后排尿日记及尿动力学参数比较,差异有统计学意义(P<0.01).比较治疗前后抑郁与焦虑的心理评分差异有统计学意义(P<0.01).结论 骶神经电刺激与辣椒辣索类似物(RTX)联合治疗可改善女性IOAB患者的排尿功能障碍,可明显改善生活质量。

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目的 分析骶神经电刺激与辣椒辣素类似物(RTX)联合治疗女性特发性膀胱过度活动症(IOAB)的疗效.方法 将32例女性IOAB患者采用经皮穿刺电刺激骶3神经及100 nmol/L RTX溶液100ml膀胱灌注治疗3个月,观察治疗前后排尿日记及尿动力学参数,并通过治疗前后抑郁与焦虑的心理评分来分析患者的生活质量有元改善.结果 治疗前后排尿日记及尿动力学参数比较,差异有统计学意义(P<0.01).比较治疗前后抑郁与焦虑的心理评分差异有统计学意义(P<0.01).结论 骶神经电刺激与辣椒辣索类似物(RTX)联合治疗可改善女性IOAB患者的排尿功能障碍,可明显改善生活质量。

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Available abstract

目的 分析骶神经电刺激与辣椒辣素类似物(RTX)联合治疗女性特发性膀胱过度活动症(IOAB)的疗效.方法 将32例女性IOAB患者采用经皮穿刺电刺激骶3神经及100 nmol/L RTX溶液100ml膀胱灌注治疗3个月,观察治疗前后排尿日记及尿动力学参数,并通过治疗前后抑郁与焦虑的心理评分来分析患者的生活质量有元改善.结果 治疗前后排尿日记及尿动力学参数比较,差异有统计学意义(P<0.01).比较治疗前后抑郁与焦虑的心理评分差异有统计学意义(P<0.01).结论 骶神经电刺激与辣椒辣索类似物(RTX)联合治疗可改善女性IOAB患者的排尿功能障碍,可明显改善生活质量。

Key concepts: Resiniferatoxin, Medicine, Overactive bladder, Urology, Sacral nerve stimulation, Gynecology, Internal medicine, Pathology

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