2016Chinese Journal of AsthmaRequires access

The impact of lower respiratory tract microbiota on the host immune system

Xiaoling Qi

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Abstract

With the development of bacterial identification technology, we know that lower respiratory tract of healthy people is not sterile.The microbiota resident in human lower respiratory tract plays the role on the mature of host immune system, which has the ability to regulate the innate immune response and adaptive immune response.When respiratory diseases developed, such as asthma and chronic obstructive pulmonary disease, micro-ecological environment of host lower respiratory tract changed, and host immune status also changed, but their relationship is not clear.Here, we would state the impact of lower respiratory tract microbiota on the host immune system, especially on the development of respiratory disease. Key words: Microbiota; Immune system; Respiratory tract diseases

About this research paper

What this paper is about

With the development of bacterial identification technology, we know that lower respiratory tract of healthy people is not sterile.The microbiota resident in human lower respiratory tract plays the role on the mature of host immune system, which has the ability to regulate the innate immune response and adaptive immune response.When respiratory diseases developed, such as asthma and chronic obstructive pulmonary disease, micro-ecological environment of host lower respiratory tract changed, and host immune status also changed, but their relationship is not clear.Here, we would state the impact of lower respiratory tract microbiota on the host immune system, especially on the development of respiratory disease. Key words: Microbiota; Immune system; Respiratory tract diseases

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Available abstract

With the development of bacterial identification technology, we know that lower respiratory tract of healthy people is not sterile.The microbiota resident in human lower respiratory tract plays the role on the mature of host immune system, which has the ability to regulate the innate immune response and adaptive immune response.When respiratory diseases developed, such as asthma and chronic obstructive pulmonary disease, micro-ecological environment of host lower respiratory tract changed, and host immune status also changed, but their relationship is not clear.Here, we would state the impact of lower respiratory tract microbiota on the host immune system, especially on the development of respiratory disease. Key words: Microbiota; Immune system; Respiratory tract diseases

Key concepts: Immune system, Respiratory tract, Medicine, Respiratory system, Immunology, Respiratory tract infections, Innate immune system, Host (biology)

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