2014•Int J BiologicalsRequires access

Recent progress towards development of a Shigella vaccine

Dong Yan, Ming Zeng

Abstract

Dysentery is a worldwide epidemic of infectious disease caused by the Shigella.Because the pathogenesis of Shigella and body immunity against infection are not very clear,there is no real practical Shigella vaccine on the market for now.This review discusses the pathogenesis of Shigella,and provides the latest developments in Shigella vaccines research,especially in subunit vaccines. Key words: Shigella dysenteriae ; Vaccines, subunit ; Adjuvants, immunologic

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Key concepts: Shigella, Shigella dysenteriae, Dysentery, Shigellosis, Virology, Immunology, Immunity, Medicine