Intravitreal injection of triamcinolone acetonide (TA) combined with laser photocoagulation treatment on diffused diabetic macular edema

Objective To investigate the effect of intmvitreal injection of triamcinolone acetonide (TA) combined with laser photocoagulation treatment on diffused diabetic macular edema. Methods 25 patients (36 eyes) with diffused diabetic macular edema diagnosed by ocular fundus examination, fundusfluorescein angiography (FFA), 18 eyes of them were treated with intravitreal injection triameinolone acetonide(TA) combined laser photoeoagulation and 18 eyes only laser photocoagulation. The follow-up time was 1, 3,and 6 months. Visual acuity and fundus fluorescein angiography were measured. Results: There wereno statistical difference in mean visual acuity and the mean central macular thickness in preoperation between two groups(P>0.05). The mean acuity in lmonth、3month and 6months after combined group was significantly higher than that of laser photocoagulation group (P<0.05). The mean central macular thickness in combined group was lower than that in the laser photocoagulation group(P<0.05). Conclusions The result ofintravitreal injection triamcinolone acetonide (TA) combined Laser photocoagulation treatment for diffused diabetic macular edemae is better than those of only using laser photocoagulation. Key words: Diabetic macular edema;  Triamcinolone aeetonide;  Intmvitreal injection;  Laser photocoagulation