2012•Guoji zhongliuxue zazhiRequires access

Hepatocyte growth factor and its receptor in multiple myeloma

Cheng-lin Hu, Lei-hua Fu, Lin Chen

Abstract

Hepatocyte growth factor ( HGF),a multifunctional cytokine,plays a biological role through acting on the cell surface transmembrane receptor c-Met.The growth,invasion and metastasis of many tumors are associated with the abnormalities of HGF-c-Met signaling pathway.Studies found that HGF and its receptor c-Met have close relations with the occurrence,metastasis,invasion and prognosis of multiple myeloma. Key words: Hepatocyte growth factor; Multiple myeloma

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Key concepts: Hepatocyte growth factor, Hepatocyte Growth Factor Receptor, Multiple myeloma, Cancer research, Metastasis, Receptor, Cytokine, Hepatocyte