2011•Zhongguo jiceng yiyaoRequires access

Effect of ICE regimen in treatment of relapsed and refractory non-Hodgkin's lymphoma

Yongzhong Liu, Jiewen Peng, Jing-huang He, Han‐lin Liang, Zhao-feng Yin

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Abstract

Objective To evaluate the short-term effect and side effects of ICE regimen treating the patients with relapsed and refractory non-Hodgkin's lymphoma(NHL). Methods Twenty-five patients with relapsed and refractory NHL were treated with ICE regimen. Treatment was repeated every 3 weeks. Results The total effective rate was 76.0% for 25 patients,The response rate(PR) was 60.0%. The main side effects were marrow suppression including of leucopenia and thrombocytopenia,no patients dead for toxic reactions of chemotherapy. Conclusion ICE regimen was a safe and effective salvage regimen for the patients with relapsed and refractory NHL. Key words: Lymphoma, non-Hodgkin;  Chemotherapy

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Objective To evaluate the short-term effect and side effects of ICE regimen treating the patients with relapsed and refractory non-Hodgkin's lymphoma(NHL). Methods Twenty-five patients with relapsed and refractory NHL were treated with ICE regimen. Treatment was repeated every 3 weeks. Results The total effective rate was 76.0% for 25 patients,The response rate(PR) was 60.0%. The main side effects were marrow suppression including of leucopenia and thrombocytopenia,no patients dead for toxic reactions of chemotherapy. Conclusion ICE regimen was a safe and effective salvage regimen for the patients with relapsed and refractory NHL. Key words: Lymphoma, non-Hodgkin;  Chemotherapy

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Available abstract

Objective To evaluate the short-term effect and side effects of ICE regimen treating the patients with relapsed and refractory non-Hodgkin's lymphoma(NHL). Methods Twenty-five patients with relapsed and refractory NHL were treated with ICE regimen. Treatment was repeated every 3 weeks. Results The total effective rate was 76.0% for 25 patients,The response rate(PR) was 60.0%. The main side effects were marrow suppression including of leucopenia and thrombocytopenia,no patients dead for toxic reactions of chemotherapy. Conclusion ICE regimen was a safe and effective salvage regimen for the patients with relapsed and refractory NHL. Key words: Lymphoma, non-Hodgkin;  Chemotherapy

Key concepts: Medicine, Regimen, Refractory (planetary science), Lymphoma, Chemotherapy, Internal medicine, Surgery, Gastroenterology

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