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The clinic characters of chronic inflammatory demyelinating polyradiculopathy in children

吴正文, 郭智超

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Abstract

目的探讨儿童慢性炎症性脱髓鞘性多发性神经病(CIDP)的临床特征及实验室改变、预后.方法对CIDP的临床资料进行分析,并对其进行随访.结果11例CIDP 3例病前有上感史;病程为2个月～1年;男性及学龄期儿童多见;均有双下肢肌力下降,双上肢肌力下降者4例,感觉障碍者6例,肌萎缩7例,颅神经麻痹1例.均有神经电生理改变,脑脊液检查除1例外均有细胞-蛋白分离现象.结论CIDP与AIDP/RGBS不同,表现为起病慢,达高峰时间长,肌萎缩、感觉障碍多见,很少伴发颅神经损害和呼吸肌麻痹.脑脊液细胞蛋白分离现象多见,电生理改变明显.坚持治疗者预后较好.

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目的探讨儿童慢性炎症性脱髓鞘性多发性神经病(CIDP)的临床特征及实验室改变、预后.方法对CIDP的临床资料进行分析,并对其进行随访.结果11例CIDP 3例病前有上感史;病程为2个月～1年;男性及学龄期儿童多见;均有双下肢肌力下降,双上肢肌力下降者4例,感觉障碍者6例,肌萎缩7例,颅神经麻痹1例.均有神经电生理改变,脑脊液检查除1例外均有细胞-蛋白分离现象.结论CIDP与AIDP/RGBS不同,表现为起病慢,达高峰时间长,肌萎缩、感觉障碍多见,很少伴发颅神经损害和呼吸肌麻痹.脑脊液细胞蛋白分离现象多见,电生理改变明显.坚持治疗者预后较好.

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Available abstract

目的探讨儿童慢性炎症性脱髓鞘性多发性神经病(CIDP)的临床特征及实验室改变、预后.方法对CIDP的临床资料进行分析,并对其进行随访.结果11例CIDP 3例病前有上感史;病程为2个月～1年;男性及学龄期儿童多见;均有双下肢肌力下降,双上肢肌力下降者4例,感觉障碍者6例,肌萎缩7例,颅神经麻痹1例.均有神经电生理改变,脑脊液检查除1例外均有细胞-蛋白分离现象.结论CIDP与AIDP/RGBS不同,表现为起病慢,达高峰时间长,肌萎缩、感觉障碍多见,很少伴发颅神经损害和呼吸肌麻痹.脑脊液细胞蛋白分离现象多见,电生理改变明显.坚持治疗者预后较好.

Key concepts: Polyradiculopathy, Medicine, Pathology

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