Research Progress of Fertilization Regulation Mechanism
Pinxiu Huang
Abstract
Pinxiu Huang
Abstract
The mechanism of human and mammalian fertilization has been the hot subject in recent years. The fertilization mechanisms according to biochemistry, transgenic and gene knock-out are the following four major aspects, ①sperm capacitation; ②sperm to the ovum zona pellucida; ③sperm combined zona pellucida induced acrosome reaction (AR) ; ④sperm combined ovum and membrane fusion. This paper focuses on the research progress of sperm capacitation, AR, and sperm-ovum fusion. Key words: Fertilization mechanism; Sperm capacitation; Acrosome reaction; Sperm-ovum fusion
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The mechanism of human and mammalian fertilization has been the hot subject in recent years. The fertilization mechanisms according to biochemistry, transgenic and gene knock-out are the following four major aspects, ①sperm capacitation; ②sperm to the ovum zona pellucida; ③sperm combined zona pellucida induced acrosome reaction (AR) ; ④sperm combined ovum and membrane fusion. This paper focuses on the research progress of sperm capacitation, AR, and sperm-ovum fusion. Key words: Fertilization mechanism; Sperm capacitation; Acrosome reaction; Sperm-ovum fusion
Key concepts: Capacitation, Human fertilization, Sperm, Zona pellucida, Acrosome reaction, Andrology, Acrosome, Cell biology