To investigate the effects of CO2 pneumoperitoneum pressure in neonates and younger infants undergoing laparoscopy

Objective To investigate the effects of CO2 pneumoperitoneum pressure with primary physiological indexes in neonates and younger infants undergoing laparoscopy.Methods Twenty patients(group A)undergoing laparoscopic surgery were monitored using abdominal circumference,heart rate (HR),Mean aterial pressure (MAP),oxygen saturation (SiO2),end tidal CO2 (PETCO2),before pneumoperitoneum.during pneumoperitoneum with pressure at 5 mmHg and 10 mmHg.In thirty other patients (group B) undergoing laparoscopic surgery,pneumoperitoneum pressurewas increased from 6 mmHg upwards until PETCO2 achieved or surpassed 50 mmHg,and this pressure was the patient's feasible pneumoperitoneum pressure.Results PETCO2 was usually lower than 50 mmHg when CO2 pneumoperitoneum pressure was 5 mmHg in group A.Abdominal cavity volume would be increased by 35％ when pneumoperitoneum pressure was 5 mmHg,while an extra 11％ abdominal cavity volume was achieved at 10 mmHg.Individual pneumoperitoneum pressurewascorrelated with height,weight,age and kaup indexin group B,the regression function was:pneumoperitoneum pressure =3.926 + 1.468 × weight,using multiple regression method.Conclusions The function was suitable for patients younger than three-month with normal cardiopulmonary function,and the pneumoperitoneum pressure should be adjusted accordingto PETCO2. Key words: Neonate;  Laparoscopes;  Respiration;  CO2 ;  Pressure