Risk factors related to incidence of shunt dependent hydrocephalus in patients with intracranial aneurysmal subarachnoid hemorrhage

Objective To analyze the risk factors related to incidence of shunt dependent hydrocephalus in patients with intracranial aneurysmal subarachnoid hemorrhage so as to provide guidance for clinical diagnosis and treatment. Methods The clinical data were retrospectively analyzed of the 451 patients who had been treated in our hospital for ruptured intracranial aneurysmal subarachnoid hemorrhage from January 2013 to December 2016. Of them, 67 were complicated with shunt dependent hydrocephalus and 384 were not. The 2 groups were compared in terms of related clinical variables. Multivariate Logistic regression was conducted to analyze risk factors associated with incidence of shunt dependent hydrocephalus. Results The proportions of patients >60 years old, intraventricular hemorrhage, posterior circulation aneurysm, acute hydrocephalus and central nervous system infection were significantly higher in the patients with complicated shunt dependent hydrocephalus than in those without (P<0.05). There were significant differences between the 2 groups in Hunt-Hess grade and Fisher grade at admission (P<0.05). Multivariate Logistic regression analysis revealed that posterior circulation aneurysm, acute hydrocephalus and central nervous system infection were independent risk factors for incidence of shunt dependent hydrocephalus in patients with intracranial aneurysmal subarachnoid hemorrhage. Conclusion If the patients with intracranial aneurysmal subarachnoid hemorrhage are complicated with posterior circulation aneurysm, acute hydrocephalus and central nervous system infection, they are more likely to develop shunt dependent hydrocephalus. Key words: Intracranial aneurysm; Subarachnoid hemorrhage; Shunt dependent hydrocephalus; Influencing factors