Clinical value of single contrast-enhanced ultrasound, ultrasonic elastography and combined detection of the two methods in diagnosis of breast cancer

Objective To analyze the clinical value of single contrast-enhanced ultrasound or combined with ultrasonic elastography in diagnosis of breast cancer. Methods A total of 108 patients with breast mass resection (137 breast masses) in Nanyang Hospital of Traditional Chinese Medicine from January 2017 to December 2017 were selected, and they were given contrast-enhanced ultrasound and ultrasonic elastography examination. The diagnostic results of contrast-enhanced ultrasound and ultrasonic elastography were observed. The pathological diagnosis results were taken as the gold standard. The sensitivity, specificity, accuracy of contrast-enhanced ultrasound and ultrasonic elastography in diagnosis of breast cancer were recorded. Results Confirmed by pathological diagnosis, there were 48 malignant masses and 89 benign masses in 137 breast masses. The pathological results were taken as the gold standard, the sensitivity, specificity, accuracy of contrast-enhanced ultrasound in diagnosis of breast mass were 79.17%, 80.90%, 80.29%. The sensitivity, specificity, accuracy of ultrasonic elastography in diagnosis of breast mass were 77.08%, 82.02%, 80.29%. The sensitivity, specificity, accuracy ofcontrast-enhanced ultrasound combined with ultrasonic elastography in diagnosis of breast mass were 95.83%, 92.13%, 92.75%. There was no significant difference in the sensitivity, specificity, accuracy between contrast-enhanced ultrasound and ultrasonic elastography (P>0.05). Compared with single contrast-enhanced ultrasound or ultrasonic elastography, the sensitivity, specificity, accuracy of contrast-enhanced ultrasound combined with ultrasonic elastography in diagnosis of breast mass were higher (P<0.05). Conclusions Contrast-enhanced ultrasound and ultrasonic elastography in the diagnosis of breast cancer have certain value, and the combined application can increase the diagnostic efficiency for breast cancer. Key words: Breast cancer; Contrast-enhanced ultrasound; Ultrasonic elastography; Diagnostic value