Pathogenesis of psoriasis and metabolic syndrome: an update

Psoriasis and metabolic syndrome are two common clinical conditions,and often occur concurrently.Psoriasis is a chronic,relapsing,multifactorial inflammatory skin disease,whose pathogenesis is associated with genetic factors,immunological factors,infection,smoking,mental stress and other environmental factors.Metabolic syndrome is a pathological condition primarily presenting as central obesity accompanied by hyperglycemia,hypertension,lipid disorders and other metabolic abnormalities.The pathogenesis of psoriasis is closely related to that of metabolic syndrome,and some cytokines are simultaneously involved in their pathogenesis.To study metabolic syndrome may provide new targets for the treatment of psoriasis. Key words: Psoriasis;  Metabolic syndrome;  Pathogenesis