2019Chin J Reprod ContracepRequires access

Ovulation induction in the treatment of patients with polycystic ovary syndrome

Wenjin Gan, Gang Li

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Abstract

Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder in women of reproductive age, but the pathogenesis is still unknown. At present, most studies suggest that insulin resistance, hyperandrogenism, neuroendocrine and inflammatory factors play important roles in the pathogenesis of PCOS. PCOS-related anovulation is an important reason of female infertility. For PCOS with infertility, ovulation induction is an essential method to assisted reproduction. Therefore, we reviewed the development of the studies of PCOS-related anovulation and ovulation induction therapy, and discussed the role of ovulation induction therapy for PCOS with infertility. Key words: Polycystic ovary syndrome; Ovulation failure; Ovulation induction

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What this paper is about

Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder in women of reproductive age, but the pathogenesis is still unknown. At present, most studies suggest that insulin resistance, hyperandrogenism, neuroendocrine and inflammatory factors play important roles in the pathogenesis of PCOS. PCOS-related anovulation is an important reason of female infertility. For PCOS with infertility, ovulation induction is an essential method to assisted reproduction. Therefore, we reviewed the development of the studies of PCOS-related anovulation and ovulation induction therapy, and discussed the role of ovulation induction therapy for PCOS with infertility. Key words: Polycystic ovary syndrome; Ovulation failure; Ovulation induction

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Available abstract

Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder in women of reproductive age, but the pathogenesis is still unknown. At present, most studies suggest that insulin resistance, hyperandrogenism, neuroendocrine and inflammatory factors play important roles in the pathogenesis of PCOS. PCOS-related anovulation is an important reason of female infertility. For PCOS with infertility, ovulation induction is an essential method to assisted reproduction. Therefore, we reviewed the development of the studies of PCOS-related anovulation and ovulation induction therapy, and discussed the role of ovulation induction therapy for PCOS with infertility. Key words: Polycystic ovary syndrome; Ovulation failure; Ovulation induction

Key concepts: Anovulation, Polycystic ovary, Ovulation induction, Hyperandrogenism, Infertility, Ovulation, Medicine, Endocrinology

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