New progress of anti-Müllerian in clinical research and application

Anti-Mullerian hormone (AMH) is one of important regulation factors of the female reproductive physiological. It is mainly secreted by the preantral follicles and small antral follicles and out-controlled by the gonadotropins (Gn), could inhibit the recruitment, chosen of follicles, and development of the advantage follicles. Because of its relatively stable serum level throughout the whole menstrual cycle and could be detected any time in the menstrual, AMH has an important value in diagnosing and treatment of polycystic ovary syndrome (PCOS) and ovarian hyperstimulation syndrome (OHSS); furthermore, it has a certain value in ovarian reserve function, pregnancy rates of in vitro fertilization embryo transfer (IVF-ET) and ovarian tumor, also provides a reliable basis for ovarian tumor’s follow-up. Key words: Anti-Mullerian hormone (AMH); Ovarian reserve function; Polycystic ovary syndrome (PCOS); In vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) outcome; Ovarian tumor