2013•Int J GenetRequires access
Research progress in non-invasive prenatal aneuploidy diagnosis using fetal free nucleic acids in maternal plasma
Huakun Zhang, Wenjie Zhu
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Abstract
Recent reports have proved that fetal free nucleic acids can be detected in maternal plasma.Recent technical advances of non-invasive prenatal aneuploidy diagnosis using free fetal DNA and RNA have led to a major change in the clinical application and potential usefulness of this technique.This paper aims to review the advances in the non-invasive prenatal diagnosis using free fetal DNA and RNA in maternal plasma of pregnant women.
Key words:
Non-invasive prenatal diagnosis; Fetal free DNA; Fetal free RNA; Chromosomal aneuploidy