Effect of phacoemulsification and intraocular lens implantation combined with vitrectomy on the dynamic changes of intraocular pressure

Objective To investigate the effect of phacoemulsification and intraocular lens implantation combined with vitrectomy on the dynamic changes of intraocular pressure.Methods A sample of 73 eyes of 70 patients was divided into two groups according to the operation method.Phacoemulsification and intraocular lens combined with vitrectomy implantation performed on 38 eyes of 37 patients (study group) were compared with vitrectomy alone performed on 35 eyes of 33 patients (control group).The dynamic changes of intraocular pressure 1,2,3 days,1,3 weeks,1,2,3 months after surgery were observed.Results The intraocular pressure was peaked on the 1st day after surgery in control group from ( 13.7 ± 2.2)mm Hg ( 1 mm Hg =0.133 kPa) preoperatively to ( 18.5 ± 6.9) mm Hg postoperatively,and recovered the preoperative level on the 3rd day after surgery.The intraocular pressure was peaked on the 1st day after surgery in study group from ( 12.9 ± 2.4) mm Hg preoperatively to (23.4 ± 8.0) mm Hg postoperatively,and recovered the preoperative level on the 3rd week after surgery.The intraocular pressure in both groups displayed an significant elevation on postoperative days,although degree of intraocular pressure elevation in study group was higher than that in control group (P ＜0.05).The correlation analysis showed:diabetic retinopathy,and combined with cataract extraction and lens implantation were independent risk factors of intraocular pressure surge (the intraocular pressure ≥10 mm Hg) after vitrectomy. Conclusions Phacovitrectomy and intraocular lens implantation increases the risk of transient intraocular pressure elevation in early postoperative stage than vitrectomy alone.The patients who are vulnerable to intraocular pressure fluctuations when performed a combined surgery should be paid more attention. Key words: Vitrectomy;  Phacoemulsification;  Intraocular pressure