2011Guoji zhongliuxue zazhiRequires access

Circulating tumor cells in breast cancer

Hongyan Huang, Zefei Jiang

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Abstract

Circulating tumor cells (CTCs) in breast cancer patients can be detected by Cell Search system. Results from recent studies suggested that CTCs level might serve as a prognostic marker and be used in the early assessment of therapeutic response in patients with metastatic breast cancer. However the role of CTCs in early stage breast cancer is not well established. Large prospective trials are needed to further understand its biological characteristics and to confirm its role as a predictive and prognostic marker. Key words: Breast neoplasms;  Neoplasm circulating cells;  Forecasting

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What this paper is about

Circulating tumor cells (CTCs) in breast cancer patients can be detected by Cell Search system. Results from recent studies suggested that CTCs level might serve as a prognostic marker and be used in the early assessment of therapeutic response in patients with metastatic breast cancer. However the role of CTCs in early stage breast cancer is not well established. Large prospective trials are needed to further understand its biological characteristics and to confirm its role as a predictive and prognostic marker. Key words: Breast neoplasms;  Neoplasm circulating cells;  Forecasting

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Available abstract

Circulating tumor cells (CTCs) in breast cancer patients can be detected by Cell Search system. Results from recent studies suggested that CTCs level might serve as a prognostic marker and be used in the early assessment of therapeutic response in patients with metastatic breast cancer. However the role of CTCs in early stage breast cancer is not well established. Large prospective trials are needed to further understand its biological characteristics and to confirm its role as a predictive and prognostic marker. Key words: Breast neoplasms;  Neoplasm circulating cells;  Forecasting

Key concepts: Circulating tumor cell, Breast cancer, CA15-3, Medicine, Oncology, Metastatic breast cancer, Neoplasm, Internal medicine

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