Progress on the association between hepatitis B virus and hepatocellular carcinoma
Fu-Long Hao, Huilai Miao
Abstract
Fu-Long Hao, Huilai Miao
Abstract
Chronic hepatitis B virus is the most common cause of hepatocellular carcinoma. This article summarizes the pathogenesis of HBV-related carcinogenesis and the viral and host factors that may increase the risk of HCC development. HBV has 40RFs (S,C,P,X). The approach associated with HBV-related hepatocarcinogenesis includes paint mutation, insertion mutation and deletion mutations. Key words: hepatitis B virus; genetic mutation; hepatocellular carcinoma
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Chronic hepatitis B virus is the most common cause of hepatocellular carcinoma. This article summarizes the pathogenesis of HBV-related carcinogenesis and the viral and host factors that may increase the risk of HCC development. HBV has 40RFs (S,C,P,X). The approach associated with HBV-related hepatocarcinogenesis includes paint mutation, insertion mutation and deletion mutations. Key words: hepatitis B virus; genetic mutation; hepatocellular carcinoma
Key concepts: Hepatocellular carcinoma, Hepatitis B virus, Mutation, Virology, Carcinogenesis, Virus, Pathogenesis, Hepatitis B