2011•Guoji zhongliuxue zazhiRequires access
Aberrant methylation in lung cancer
胡林, 苏丹, 张沂平
Open publisher page 0 citations
Abstract
Aberrant promoter methylation in special genes such as tumor suppressor genes is early eventin carcinogenesis of lung cancer. Aberrant methylation, resulting in corresponding mRNA silence or overexpression , closely relates to carcinogenesis, development, treatment response and prognosis of lung cancer and it may become a potential biomarker. Methylation of special genes may provide evidences for individual treatment of lung cancers.
Key words:
Methylation ; Lung neoplasms ; Tumor markers,biological ;