钱宜珊, 褚仁远
Abstract
Sonic Hedgehog(Shh)信号通路在脊椎动物眼球发育过程中发挥重要的调控作用.包括决定视泡发育模式,促进神经元、神经胶质细胞及视网膜色素上皮细胞分化,调节细胞增生和存活,决定视网膜分层结构,引导视茎和轴突发育等.Shh可能参与角膜上皮细胞的增生和修复过程,并可能参与近视及眼部新生血管的调控。
A significance statement is not available in the OpenAlex record.
A contribution statement is not available in the OpenAlex record.
Method details are not available in the OpenAlex metadata.
Findings are not separately available in the OpenAlex metadata.
Limitations are not available in the OpenAlex metadata.
Application details are not available in the OpenAlex metadata.
Sonic Hedgehog(Shh)信号通路在脊椎动物眼球发育过程中发挥重要的调控作用.包括决定视泡发育模式,促进神经元、神经胶质细胞及视网膜色素上皮细胞分化,调节细胞增生和存活,决定视网膜分层结构,引导视茎和轴突发育等.Shh可能参与角膜上皮细胞的增生和修复过程,并可能参与近视及眼部新生血管的调控。
Key concepts: Vertebrate, Eye development, Sonic hedgehog, Biology, Optometry, Communication, Computer science, Signal transduction