Investigation on microsurgery for craniopharyngioma

Objective To study microsurgery for craniopharyngioma and factors of influencing prognosis . Methods 62 cases with craniopharyngioma through microsurgery were enrolled as research subjects .According to the tumor characteristics,they were used through pterional,subfrontal approach,endplate and a lateral frontal approach . Results The tumor resection was 40 cases,12 cases of subtotal resection ,10 cases of subtotal .38 cases of pituitary stalk were reserved,cutting 9 cases,not-identified 15 cases.Postoperative blood electrolyte imbalance was 33 cases, 15 cases of mild to moderate diabetes insipidus ,seizures 1 case,1 case of persistent fever coma .Postoperative follow-up 6 months to 72 months,57 cases was followed up,5 cases were lost.56 cases could have normal life ,study and work.Vision was restored in 53 cases,2 cases unchanged ,down 1 case.A total of 9 cases were recured during follow-up,no recurrence total resection ,subtotal resection recurrence in 2 cases,subtotal resection recurrence seven cases （to-tal resection and subtotal resection χ2 =4.28,P〈0.05;subtotal gastrectomy and subtotal resection ,χ2 =6.27,P〈0.05）.Follow-up of 37 cases of purely suprasellar tumor recurrence in 4 cases,the saddle 20 cases,5 cases of recur-rence,there was a significant difference between the two groups （t=5.08,P〈0.05）.57 patients preoperatively ele-vated CRP 32 cases,6 cases of recurrence,CRP normal 25 cases,3 cases of recurrence,there was a significant differ-ence between the two groups（t=4.96,P〈0.05）.Conclusion Selecting the appropriate surgical approach and pro-tecting the hypothalamus and pituitary stalk during the surgery were critical .Resection,tumor location,and tumor in-flammation were prognostic factors . Key words: craniopharyngioma; Microsurgery