Clinical analysis of 34 patients with acute pancreatitis in pregnancy

Objective To investigate how acute pancreatitis affect the pregnancy outcome. Methods A retrospective study was conducted in 34 pregnant women with acute pancreatitis in The First Affiliated Hospital of Sun Yat-sen University from January 2001 to January 2017. The patients were divided into mild acute pancreatitis (MAP) group (23 cases) and severe acute pancreatitis (SAP) group (11 cases), and the general information, clinical symptoms, treatment and pregnancy outcome were analyzed. Results The incidence of hyperlipidemia and neonatal asphyxia in SAP group were (7/11 cases) and (3/11 cases), which were significantly higher than those in MAP group (4/23) and (1/23), P=0.016 and P=0.038, respectively. Compare with MAP group, the gestational weeks of delivery in SAP group was lower (32.7±5.6 weeks vs 37.0±3.8 weeks, P=0.035). There was no statistical significance of other indicators in the two groups. Conclusions SAP was associated with higher triglyceride and hyperlipidemia. SAP is the serious condition and harm to maternal-fetal heath seriously, so the level of blood lipids should be monitored and controlled strictly during pregnancy. Key words: Pregnancy, high-risk; Pancreatitis, acute necrotizing; Hyperlipidemias