[Effects of blueberry on hepatic fibrosis and expression of nuclear transcription factor-кB in rats].
B F Zhang, M L Cheng, Y P Wang, Q Zhang, Li Yu, Xitong Zhao, M Mu, Y Liu
Abstract
B F Zhang, M L Cheng, Y P Wang, Q Zhang, Li Yu, Xitong Zhao, M Mu, Y Liu
Abstract
Blueberries have preventive effect on CCl4-induced hepatic fibrosis in rats, and its preventive mechanism may inhibit the expression and activation of NF-κBp65 in hepatocytes, thereby reducing TGFβ1- mediated production or activation.
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Blueberries have preventive effect on CCl4-induced hepatic fibrosis in rats, and its preventive mechanism may inhibit the expression and activation of NF-κBp65 in hepatocytes, thereby reducing TGFβ1- mediated production or activation.
Key concepts: Carbon tetrachloride, Western blot, H&E stain, Immunohistochemistry, Hepatic stellate cell, CCL4, Hepatic fibrosis, Saline