2018•PubMedOpen access

[Effects of blueberry on hepatic fibrosis and expression of nuclear transcription factor-кB in rats].

B F Zhang, M L Cheng, Y P Wang, Q Zhang, Li Yu, Xitong Zhao, M Mu, Y Liu

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Abstract

Blueberries have preventive effect on CCl4-induced hepatic fibrosis in rats, and its preventive mechanism may inhibit the expression and activation of NF-κBp65 in hepatocytes, thereby reducing TGFβ1- mediated production or activation.

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What this paper is about

Blueberries have preventive effect on CCl4-induced hepatic fibrosis in rats, and its preventive mechanism may inhibit the expression and activation of NF-κBp65 in hepatocytes, thereby reducing TGFβ1- mediated production or activation.

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Available abstract

Blueberries have preventive effect on CCl4-induced hepatic fibrosis in rats, and its preventive mechanism may inhibit the expression and activation of NF-κBp65 in hepatocytes, thereby reducing TGFβ1- mediated production or activation.

Key concepts: Carbon tetrachloride, Western blot, H&E stain, Immunohistochemistry, Hepatic stellate cell, CCL4, Hepatic fibrosis, Saline

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[Effects of blueberry on hepatic fibrosis and expression of nuclear transcription factor-кB in rats]. — Research Paper | ScholarLens