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[Prevalence of acute symptomatic seizure after intracerebral hemorrhage].

Olesya I Borovik, Taras Studeniak

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Abstract

OBJECTIVE: Introduсtion: Acute symptomatic seizure (ASS) is a most frequently complication after a stroke. Seizures could be associated with the worse outcome. Nowadays the prophylactic antiepileptic treatment after the stroke is not advisable. However this question have to be discussed in a particular groups of patients. The aim: To study the prevalence of ASS in the particular groups of patients after intracerebral hemorrhage as well as to determine the predictors of the sizure occurrence in these groups of patients. PATIENTS AND METHODS: Materials and methods: The retrospective analysis of the clinical features of intracerebral hemorrhage for 305 patients was performed. Among them there were 127 patients with aneurysmal subarachnoid hemorrhage as well as 178 patients were with nonaneurysmal intracerebral hemorrhage. RESULTS: Results: In 12 patients from 127 with subarachnoid hemorrhage were occurred onset seizures. 4 patients from 12 with subarachnoid hemorrhage died (28.5% of all deaths in the group of patients with subarachnoid hemorrhage (SAH)). In the group of patients with seizures 10 of them had aneurysm in anterior part of Willi's Circle. In 11 patients from 178 with nonaneurysmal intracerebral hemorrhage occurred onset seizures. Only one patient from 72 with medial localization of intracerebral hemorrhage had seizures. CONCLUSION: Conclusions: Prevalence of ASS after intracerebral hemorrhage reaches 7.5%, in the group of patients with SAH - 9.5%, in the group of patients with intracerebral nonaneurysmal hemorrhage - 6.25%. Initial seizures at the onset of subarachnoid hemorrhage is an unfavorable prognostic criteria and is associated with higher mortality. Localization of aneurysm in anterior part of Willi's Circle and lateral localisation of intracerebral hemorrhage are associated with a higher risk of the ASS development.

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OBJECTIVE: Introduсtion: Acute symptomatic seizure (ASS) is a most frequently complication after a stroke. Seizures could be associated with the worse outcome. Nowadays the prophylactic antiepileptic treatment after the stroke is not advisable. However this question have to be discussed in a particular groups of patients. The aim: To study the prevalence of ASS in the particular groups of patients after intracerebral hemorrhage as well as to determine the predictors of the sizure occurrence in these groups of patients. PATIENTS AND METHODS: Materials and methods: The retrospective analysis of the clinical features of intracerebral hemorrhage for 305 patients was performed. Among them there were 127 patients with aneurysmal subarachnoid hemorrhage as well as 178 patients were with nonaneurysmal intracerebral hemorrhage. RESULTS: Results: In 12 patients from 127 with subarachnoid hemorrhage were occurred onset seizures. 4 patients from 12 with subarachnoid hemorrhage died (28.5% of all deaths in the group of patients with subarachnoid hemorrhage (SAH)). In the group of patients with seizures 10 of them had aneurysm in anterior part of Willi's Circle. In 11 patients from 178 with nonaneurysmal intracerebral hemorrhage occurred onset seizures. Only one patient from 72 with medial localization of intracerebral hemorrhage had seizures. CONCLUSION: Conclusions: Prevalence of ASS after intracerebral hemorrhage reaches 7.5%, in the group of patients with SAH - 9.5%, in the group of patients with intracerebral nonaneurysmal hemorrhage - 6.25%. Initial seizures at the onset of subarachnoid hemorrhage is an unfavorable prognostic criteria and is associated with higher mortality. Localization of aneurysm in anterior part of Willi's Circle and lateral localisation of intracerebral hemorrhage are associated with a higher risk of the ASS development.

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Available abstract

OBJECTIVE: Introduсtion: Acute symptomatic seizure (ASS) is a most frequently complication after a stroke. Seizures could be associated with the worse outcome. Nowadays the prophylactic antiepileptic treatment after the stroke is not advisable. However this question have to be discussed in a particular groups of patients. The aim: To study the prevalence of ASS in the particular groups of patients after intracerebral hemorrhage as well as to determine the predictors of the sizure occurrence in these groups of patients. PATIENTS AND METHODS: Materials and methods: The retrospective analysis of the clinical features of intracerebral hemorrhage for 305 patients was performed. Among them there were 127 patients with aneurysmal subarachnoid hemorrhage as well as 178 patients were with nonaneurysmal intracerebral hemorrhage. RESULTS: Results: In 12 patients from 127 with subarachnoid hemorrhage were occurred onset seizures. 4 patients from 12 with subarachnoid hemorrhage died (28.5% of all deaths in the group of patients with subarachnoid hemorrhage (SAH)). In the group of patients with seizures 10 of them had aneurysm in anterior part of Willi's Circle. In 11 patients from 178 with nonaneurysmal intracerebral hemorrhage occurred onset seizures. Only one patient from 72 with medial localization of intracerebral hemorrhage had seizures. CONCLUSION: Conclusions: Prevalence of ASS after intracerebral hemorrhage reaches 7.5%, in the group of patients with SAH - 9.5%, in the group of patients with intracerebral nonaneurysmal hemorrhage - 6.25%. Initial seizures at the onset of subarachnoid hemorrhage is an unfavorable prognostic criteria and is associated with higher mortality. Localization of aneurysm in anterior part of Willi's Circle and lateral localisation of intracerebral hemorrhage are associated with a higher risk of the ASS development.

Key concepts: Medicine, Intracerebral hemorrhage, Subarachnoid hemorrhage, Aneurysm, Complication, Anesthesia, Stroke (engine), Retrospective cohort study

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