2018•PubMedRequires access

[The effects of Xuebijing injection on apoptosis and expression of regulatory factors TNF-α、NF-κB and Caspase-3 expression in the lung tissues of acute paraquat-induced rats].

X Wang, A J Li, W Z Li, Wei Jie Lu, Wenwen Cui

Abstract

Apoptosis and TNF-alpha, NF-kappa B and Caspase-3 play an important role in lung injury of paraquat-induced rats. Xuebijing injection can inhibit the expression of TNF-alpha, NF-kappa B, Caspase-3 in lung tissue, reduce the apoptosis rate and alleviate the damage of lung tissue in paraquat-poisoning rats.

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Available abstract

Key concepts: TUNEL assay, Apoptosis, Tumor necrosis factor alpha, Intraperitoneal injection, Caspase 3, Necrosis, Paraquat, Lung