2019PubMedRequires access

[Regulation of hypoxia inducible factor-1α on permeability of vascular endothelial cells and the mechanism].

Delin Hu, Youxin Yu, Rong Liang, Shunying Zhou, Shengliang Duan, Zhiyong Jiang, Chengying Meng, Wei Jiang, Huan Wang, Yexiang Sun, Linsen Fang

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Abstract

HIF-1α up-regulates expressions of MLCK and p-MLC and down-regulates expression of ZO-1, thereby increasing the permeability of rat vascular endothelial cells.

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HIF-1α up-regulates expressions of MLCK and p-MLC and down-regulates expression of ZO-1, thereby increasing the permeability of rat vascular endothelial cells.

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Available abstract

HIF-1α up-regulates expressions of MLCK and p-MLC and down-regulates expression of ZO-1, thereby increasing the permeability of rat vascular endothelial cells.

Key concepts: Transfection, Molecular biology, Biology, Endothelial stem cell, Cell culture, Recombinant DNA, Vascular smooth muscle, Endocrinology

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[Regulation of hypoxia inducible factor-1α on permeability of vascular endothelial cells and the mechanism]. — Research Paper | ScholarLens