2017•PubMedRequires access
[Neuropathologic findings in intractable epilepsy: a clinicopathologic analysis of 822 cases].
Z J Duan, Kazuo Yao, Jian Zhou, L Li, Feifei Zhai, C Q Liu, Zhong Ma, Yuanyuan Bian, Guoming Luan, Xueling Qi
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Abstract
FCDⅢd is the most common histopathological subtype causing intractable epilepsy, mainly due to focal hypoxia/ischemia in the perinatal period, which results in scarring of local brain tissue; this is followed by other isolated forms of FCD (FCDⅠand FCDⅡ), and then FCD Ⅲa and FCD Ⅲb. The reason to distinguish isolated forms of FCD (types Ⅰ and Ⅱ) from FCD Ⅲ and to subclassify FCD Ⅲ is to allow better definition of cortical dyslamination. Therefore, the pathogenic factors of intractable epilepsy can be grouped in greater details, and facilitate the diagnosis and potential curative treatment of intractable epilepsy.