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[Effects of Different Concentrations of Glucose on the Osteogenic Differentiation of Orofacial Bone Mesenchymal Stem Cells].

Yang Chen, Yun Hu, Lan Yang, Jie Zhou, Yuying Tang, Leilei Zheng

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Abstract

OBJECTIVES: To determine the effects of different concentrations of glucose on the proliferation and osteogenic differentiation of orofacial bonemesenchymal stem cells (OFMSCs). METHODS: day. RESULTS: and Osterix mRNA in all groups showed a trend of rising first, followed by an obvious down regulation. CONCLUSIONS: With certain limits,OFMSC proliferation is promoted by glucose. Osteogenic differentiation is inhibited by glucose in a concentration-dependent manner.

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What this paper is about

OBJECTIVES: To determine the effects of different concentrations of glucose on the proliferation and osteogenic differentiation of orofacial bonemesenchymal stem cells (OFMSCs). METHODS: day. RESULTS: and Osterix mRNA in all groups showed a trend of rising first, followed by an obvious down regulation. CONCLUSIONS: With certain limits,OFMSC proliferation is promoted by glucose. Osteogenic differentiation is inhibited by glucose in a concentration-dependent manner.

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Available abstract

OBJECTIVES: To determine the effects of different concentrations of glucose on the proliferation and osteogenic differentiation of orofacial bonemesenchymal stem cells (OFMSCs). METHODS: day. RESULTS: and Osterix mRNA in all groups showed a trend of rising first, followed by an obvious down regulation. CONCLUSIONS: With certain limits,OFMSC proliferation is promoted by glucose. Osteogenic differentiation is inhibited by glucose in a concentration-dependent manner.

Key concepts: Oil Red O, RUNX2, ALIZARIN RED, Staining, Alkaline phosphatase, Mesenchymal stem cell, Chemistry, Adipogenesis

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[Effects of Different Concentrations of Glucose on the Osteogenic Differentiation of Orofacial Bone Mesenchymal Stem Cells]. — Research Paper | ScholarLens