2020•ApmisOpen access

Studies on viral pneumonia related to novel coronavirus SARS‐CoV‐2, SARS‐CoV, and MERS‐CoV: a literature review

Liya Guo, Wang Yuguang, Liu Jian, Huaiping Yuan, Xue Han, Huo Jianwei, Ma Jiaju, Youran Lu, Ming Chen, Yiqing Jiao

Abstract

Coronaviruses are a class of RNA viruses that can cause respiratory and intestinal infections in animals and humans. SARS-CoV, MERS-CoV, and a novel coronavirus (SARS-CoV-2 [2019-nCoV]) belong to the family Coronaviridae and the genus Betacoronavirus. At present, the understanding of SARS-CoV-2 is getting deeper and deeper. In order to better prevent and treat SARS-CoV-2, this article compares the infectivity, pathogenicity, and related clinical characteristics of the three human pathogenic coronaviruses, SARS-CoV-2, SARS-CoV, and MERS-CoV to help us further understand the pathogenic characteristics of novel coronaviruses.

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Key concepts: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Coronavirus disease 2019 (COVID-19), 2019-20 coronavirus outbreak, Betacoronavirus, Virology, Coronavirus, Pneumonia, Sars virus