2017•PubMedOpen access

[Effect of pregnant rat adipose-derived stem cells on repair of acute liver injury].

Junnan Li, Jiayong Chen, Zhong Chen, Hongchang Yang, Kaiyu Hou

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Abstract

Objective: To assess the effect of pregnant rat adipose-derived stem cells (ADSCs) on repair of acute liver injury. Methods: cells/mL) were injected into the spleen in groups A, C, and D respectively; rats in group B was not treated. After 7 days, total bilirubin (TBIL), alanine aminotransferase (ALT), aspartic acid transaminase (AST), albumin (ALB), and total protein (TP) in serum were measured. The liver tissue sections were stained with HE. The expressions of Ki67, alpha-fetoprotein (AFP), and ALB were measured by immunohistochemistry. Results: <0.05). Conclusion: .

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What this paper is about

Objective: To assess the effect of pregnant rat adipose-derived stem cells (ADSCs) on repair of acute liver injury. Methods: cells/mL) were injected into the spleen in groups A, C, and D respectively; rats in group B was not treated. After 7 days, total bilirubin (TBIL), alanine aminotransferase (ALT), aspartic acid transaminase (AST), albumin (ALB), and total protein (TP) in serum were measured. The liver tissue sections were stained with HE. The expressions of Ki67, alpha-fetoprotein (AFP), and ALB were measured by immunohistochemistry. Results: <0.05). Conclusion: .

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Available abstract

Objective: To assess the effect of pregnant rat adipose-derived stem cells (ADSCs) on repair of acute liver injury. Methods: cells/mL) were injected into the spleen in groups A, C, and D respectively; rats in group B was not treated. After 7 days, total bilirubin (TBIL), alanine aminotransferase (ALT), aspartic acid transaminase (AST), albumin (ALB), and total protein (TP) in serum were measured. The liver tissue sections were stained with HE. The expressions of Ki67, alpha-fetoprotein (AFP), and ALB were measured by immunohistochemistry. Results: <0.05). Conclusion: .

Key concepts: Adipose tissue, Liver injury, Albumin, Aspartate transaminase, Alanine transaminase, Internal medicine, Bilirubin, Spleen

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