FDA Acceptance of Surrogate End Points for Cancer Drug Approval: 1992-2019
Emerson Yu-sheng Chen, Alyson Haslam, Vinay K. Prasad
Abstract
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Emerson Yu-sheng Chen, Alyson Haslam, Vinay K. Prasad
Abstract
Open-access reader
This retrospective review assesses the frequency of surrogate measures used for the first time vs subsequent times in a cancer setting and the surrogate’s strength of correlation with patient-centered outcomes.
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This retrospective review assesses the frequency of surrogate measures used for the first time vs subsequent times in a cancer setting and the surrogate’s strength of correlation with patient-centered outcomes.
Key concepts: Medicine, Surrogate endpoint, Cancer drugs, Retrospective cohort study, Cancer, Drug approval, Drug, Medical physics