A COMPREHENSIVE REVIEW ON MATRIX TYPE TRANSDERMAL PATCHES
Asheesh Chauhan and Dr. Kapil Kumar
Abstract
Asheesh Chauhan and Dr. Kapil Kumar
Abstract
Transdermal drug delivery system was presented to overcome the difficulties of drug delivery especially oral route. A transdermal patch is a medicated adhesive patch that is placed on the skin to deliver a specific dose of medication through the skin and into the bloodstream. It promotes healing to an injured area of the body. Transdermal drugs are self-contained, discrete dosage form. It also provides controlled release of the drug for extended period of the time. Drug delivery through the skin to achieve a systemic effect without producing any fluctuations in plasma concentration of the drug. This review article covers introduction, outline advantages, disadvantages, skin pathways for transdermal drug delivery systems, various components of transdermal patches, preparation of transdermal patches, factor affecting transdermal patches, evaluation of transdermal system.
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Transdermal drug delivery system was presented to overcome the difficulties of drug delivery especially oral route. A transdermal patch is a medicated adhesive patch that is placed on the skin to deliver a specific dose of medication through the skin and into the bloodstream. It promotes healing to an injured area of the body. Transdermal drugs are self-contained, discrete dosage form. It also provides controlled release of the drug for extended period of the time. Drug delivery through the skin to achieve a systemic effect without producing any fluctuations in plasma concentration of the drug. This review article covers introduction, outline advantages, disadvantages, skin pathways for transdermal drug delivery systems, various components of transdermal patches, preparation of transdermal patches, factor affecting transdermal patches, evaluation of transdermal system.
Key concepts: Transdermal, Transdermal patch, Drug, Medicine, Pharmacology, Drug delivery, Delivery system, Materials science