2020•Dental Oral Biology and Craniofacial ResearchOpen access

Treatment of Nodular Fasciitis on the Front Surface of the Neck

Gagik Hakobyan, Anna Pogosyan, Gagik Hakobyan, Margarita Hovhannisyan, Martin S. Misakyan, Seda Burnazyan

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Abstract

Nodular fasciitis (NF) is a benign reactive or inflammatory condition of mesenchymal fibroblasts. Rapid growth and histological features make nodular fasciitis a mimicker of malignancies such as sarcomas, however, nodular fasciitis is a benign lesion and does not metastasize. Although the etiology of nodular fasciitis is uncertain, histopathologically, it bears a close resemblance to organizing granulation tissue, and myofibroblastic proliferation may be initiated by a local injury or local inflammatory process, which supports a reactive proliferation theory triggered by trauma. Surgical excision is recommended for diagnosis and treatment to exclude malignancy. We are hereby reporting a case of nodular fasciitis on the front surface of the neck, 86 years old patient. Tumor grew rapidly and reached 9-10 cm., and which was clinically suspected as a malignancy located. An ultrasound examination was performed. Based on the clinical and ultrasound data, it was decided to perform an extended biopsy to establish the final diagnosis it. Tumor has been removed as a solid mass. The material was sent for histopathological examination. Based on the history, clinical picture, and histopathological examination, the lesion was diagnosed as nodular fasciitis. After surgery patient expressed satisfaction with the result of treatment. In cases of nodular fasciitis, proactive efforts are needed to perform histopathologic evaluation and treatment because nodular fasciitis tends to grow rapidly.

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Nodular fasciitis (NF) is a benign reactive or inflammatory condition of mesenchymal fibroblasts. Rapid growth and histological features make nodular fasciitis a mimicker of malignancies such as sarcomas, however, nodular fasciitis is a benign lesion and does not metastasize. Although the etiology of nodular fasciitis is uncertain, histopathologically, it bears a close resemblance to organizing granulation tissue, and myofibroblastic proliferation may be initiated by a local injury or local inflammatory process, which supports a reactive proliferation theory triggered by trauma. Surgical excision is recommended for diagnosis and treatment to exclude malignancy. We are hereby reporting a case of nodular fasciitis on the front surface of the neck, 86 years old patient. Tumor grew rapidly and reached 9-10 cm., and which was clinically suspected as a malignancy located. An ultrasound examination was performed. Based on the clinical and ultrasound data, it was decided to perform an extended biopsy to establish the final diagnosis it. Tumor has been removed as a solid mass. The material was sent for histopathological examination. Based on the history, clinical picture, and histopathological examination, the lesion was diagnosed as nodular fasciitis. After surgery patient expressed satisfaction with the result of treatment. In cases of nodular fasciitis, proactive efforts are needed to perform histopathologic evaluation and treatment because nodular fasciitis tends to grow rapidly.

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Available abstract

Nodular fasciitis (NF) is a benign reactive or inflammatory condition of mesenchymal fibroblasts. Rapid growth and histological features make nodular fasciitis a mimicker of malignancies such as sarcomas, however, nodular fasciitis is a benign lesion and does not metastasize. Although the etiology of nodular fasciitis is uncertain, histopathologically, it bears a close resemblance to organizing granulation tissue, and myofibroblastic proliferation may be initiated by a local injury or local inflammatory process, which supports a reactive proliferation theory triggered by trauma. Surgical excision is recommended for diagnosis and treatment to exclude malignancy. We are hereby reporting a case of nodular fasciitis on the front surface of the neck, 86 years old patient. Tumor grew rapidly and reached 9-10 cm., and which was clinically suspected as a malignancy located. An ultrasound examination was performed. Based on the clinical and ultrasound data, it was decided to perform an extended biopsy to establish the final diagnosis it. Tumor has been removed as a solid mass. The material was sent for histopathological examination. Based on the history, clinical picture, and histopathological examination, the lesion was diagnosed as nodular fasciitis. After surgery patient expressed satisfaction with the result of treatment. In cases of nodular fasciitis, proactive efforts are needed to perform histopathologic evaluation and treatment because nodular fasciitis tends to grow rapidly.

Key concepts: Nodular fasciitis, Medicine, Malignancy, Fasciitis, Biopsy, Lesion, Histopathological examination, Physical examination

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