2020•Japanese journal of extra-corporeal technologyOpen access

Neutrophil gelatinase-associated lipocalin as an early indicator of acute kidney injury following pediatric cardiac surgery

Yoshihito Wakamatsu, Keisuke Nakanishi, Satoshi Matsushita, Go Sato, Hideaki Yasumoto, Shiori Kawasaki, Atsushi Amano

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Abstract

Early intervention can significantly improve patient outcomes in acute kidney injury (AKI). In children with underdeveloped kidneys, it takes longer than 24 hours for serum creatinine (sCr) to peak after AKI onset. Furthermore, even very subtle increases in sCr are associated with poor outcomes, making it more difficult to diagnose early AKI in pediatric cases.

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Early intervention can significantly improve patient outcomes in acute kidney injury (AKI). In children with underdeveloped kidneys, it takes longer than 24 hours for serum creatinine (sCr) to peak after AKI onset. Furthermore, even very subtle increases in sCr are associated with poor outcomes, making it more difficult to diagnose early AKI in pediatric cases.

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Available abstract

Early intervention can significantly improve patient outcomes in acute kidney injury (AKI). In children with underdeveloped kidneys, it takes longer than 24 hours for serum creatinine (sCr) to peak after AKI onset. Furthermore, even very subtle increases in sCr are associated with poor outcomes, making it more difficult to diagnose early AKI in pediatric cases.

Key concepts: Acute kidney injury, Medicine, Neutrophil gelatinase-associated lipocalin, Creatinine, Lipocalin, Cardiac surgery, Intervention (counseling), Intensive care medicine

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