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2011•Science and Technology Development JournalOpen access

STABILITY OF ‘SUBMICRON CURCUMIN’ FROM CURCUMA LONGA L. IN AQUEOUS MEDIA

Nhan Thi Hong Le, Au Thi Hai Truong, Chinh Ngoc Vuong, Nam T. S. Phan

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Abstract

Curcuma Longa L. has been considered as an excellent source of curcumin, having wide scale applications in pharmaceutical, food and cosmetic industry. However, widespread applications of this relatively efficacious agent have been limited due to the poor aqueous solubility, and consequently, minimal systemic bioavailability. In this research, ‘submicron curcumin’ suspension in aqueous media was prepared from Curcuma longa L. without the presence of any additive. The average diameter of the ‘submicron curcumin’ particles was 546 nm (DLS). It was found that the ‘submicron curcumin’ suspension could be used in conjunction with several common food ingredients with its stability remaining unaffected. As the system only contained ‘submicron curcumin’ and water, it would be highly promising to applications in functional food, cosmetic, and pharmaceutical industries.

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What this paper is about

Curcuma Longa L. has been considered as an excellent source of curcumin, having wide scale applications in pharmaceutical, food and cosmetic industry. However, widespread applications of this relatively efficacious agent have been limited due to the poor aqueous solubility, and consequently, minimal systemic bioavailability. In this research, ‘submicron curcumin’ suspension in aqueous media was prepared from Curcuma longa L. without the presence of any additive. The average diameter of the ‘submicron curcumin’ particles was 546 nm (DLS). It was found that the ‘submicron curcumin’ suspension could be used in conjunction with several common food ingredients with its stability remaining unaffected. As the system only contained ‘submicron curcumin’ and water, it would be highly promising to applications in functional food, cosmetic, and pharmaceutical industries.

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Available abstract

Curcuma Longa L. has been considered as an excellent source of curcumin, having wide scale applications in pharmaceutical, food and cosmetic industry. However, widespread applications of this relatively efficacious agent have been limited due to the poor aqueous solubility, and consequently, minimal systemic bioavailability. In this research, ‘submicron curcumin’ suspension in aqueous media was prepared from Curcuma longa L. without the presence of any additive. The average diameter of the ‘submicron curcumin’ particles was 546 nm (DLS). It was found that the ‘submicron curcumin’ suspension could be used in conjunction with several common food ingredients with its stability remaining unaffected. As the system only contained ‘submicron curcumin’ and water, it would be highly promising to applications in functional food, cosmetic, and pharmaceutical industries.

Key concepts: Curcumin, Curcuma, Bioavailability, Aqueous suspension, Aqueous solution, Solubility, Chemistry, Aqueous medium

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