[Effects of Thapsigargin on Intracellular Ca2+ and Caspase-3 Protein Expression in Mouse Lung Fibroblast].
Yu Yan, Kun Xiao, Xiao-Fei Liang, Meng-Rou Zhang, Kai-Xuan Mao, Fan Feng, Yonghong Xiao
Abstract
Yu Yan, Kun Xiao, Xiao-Fei Liang, Meng-Rou Zhang, Kai-Xuan Mao, Fan Feng, Yonghong Xiao
Abstract
OBJECTIVE: and the expression of caspase-3 protein in mouse lung fibroblast. METHODS: level was detected with laser confocal microscope,the protein expression of caspase-3 was examined using immunohistochemistry method. RESULTS: <0.05). CONCLUSION: TG could cause intracellular calcium dysregulation in mouse lung fibroblasts,increase caspase-3 protein expression and promote cell apoptosis.
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OBJECTIVE: and the expression of caspase-3 protein in mouse lung fibroblast. METHODS: level was detected with laser confocal microscope,the protein expression of caspase-3 was examined using immunohistochemistry method. RESULTS: <0.05). CONCLUSION: TG could cause intracellular calcium dysregulation in mouse lung fibroblasts,increase caspase-3 protein expression and promote cell apoptosis.
Key concepts: Thapsigargin, Fibroblast, Apoptosis, Molecular biology, Intracellular, Chemistry, Biology, Internal medicine