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2020•Journal of Emerging Technologies and Innovative ResearchRequires access

Pharmacological Effect of Dried Leaf Extract of Moringa oleifera on experimentally induced Hypothyroidism in Albino Rats

Shalu Tomar, Yogita Singh, Shaily Tyagi, Rahul Prabhakar

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Abstract

The dried leaf extract of Moringa oleifera was evaluated for its ameliorative effect in the regulation of hypothyroidism in rat model. Male and female albino rats of 150-200 g were treated orally with the dose of 250mg/kg body weight and 500mg/kg body weight of alcoholic extract of dried Moringa oleifera leaf. Results show that T3 and T4 were increased and TSH was decreased significantly (p˂0.0005) at high doses compared to those in the control group. The result of this study suggest that the extract may have beneficial effect on thyroid functions.

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What this paper is about

The dried leaf extract of Moringa oleifera was evaluated for its ameliorative effect in the regulation of hypothyroidism in rat model. Male and female albino rats of 150-200 g were treated orally with the dose of 250mg/kg body weight and 500mg/kg body weight of alcoholic extract of dried Moringa oleifera leaf. Results show that T3 and T4 were increased and TSH was decreased significantly (p˂0.0005) at high doses compared to those in the control group. The result of this study suggest that the extract may have beneficial effect on thyroid functions.

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Available abstract

The dried leaf extract of Moringa oleifera was evaluated for its ameliorative effect in the regulation of hypothyroidism in rat model. Male and female albino rats of 150-200 g were treated orally with the dose of 250mg/kg body weight and 500mg/kg body weight of alcoholic extract of dried Moringa oleifera leaf. Results show that T3 and T4 were increased and TSH was decreased significantly (p˂0.0005) at high doses compared to those in the control group. The result of this study suggest that the extract may have beneficial effect on thyroid functions.

Key concepts: Moringa, Body weight, Traditional medicine, Thyroid, Medicine, Biology, Chemistry, Internal medicine

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Pharmacological Effect of Dried Leaf Extract of Moringa oleifera on experimentally induced Hypothyroidism in Albino Rats — Research Paper | ScholarLens