2020Indian Journal of Pharmaceutical SciencesOpen access

Chemical Compositions and Anticancer Potential of`Essential Oil from Greenhouse-cultivated Ocimum basilicum Leaves

Talal Aburjaı, Kamal Mansi, Hanan Azzam, Dana A. Alqudah, Walhan Alshaer, M. ABUIRJEI

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Abstract

In the current study, the compositions of the essential oil obtained from leaves of Ocimum basilicum ‘Cinnamon’ grown in Jordan in a greenhouse was analysed. The antitumor activity of the essential oil was examined against three different cancer cell lines including MDA-MB-231, MCF7 and U-87 MG. The hydrodistillation method was used to extract the essential oil from Ocimum basilicum and the chemical components were analyzed and identified using gas chromatography-mass spectroscopy. The dry weight yield of essential oil was 0.50 % (w/w). Thirty-one components representing 97.80 % of the essential oil were identified. The main chemical components revealed the presence of linalool, eugenol, eucalyptol, hinesol, trans-α-bergamotene and γ-cadinene as the major constituents. In conclusion, the essential oil extracted from greenhouse cultivated Ocimum basilicum European chemotype showed potent antitumor activity.

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In the current study, the compositions of the essential oil obtained from leaves of Ocimum basilicum ‘Cinnamon’ grown in Jordan in a greenhouse was analysed. The antitumor activity of the essential oil was examined against three different cancer cell lines including MDA-MB-231, MCF7 and U-87 MG. The hydrodistillation method was used to extract the essential oil from Ocimum basilicum and the chemical components were analyzed and identified using gas chromatography-mass spectroscopy. The dry weight yield of essential oil was 0.50 % (w/w). Thirty-one components representing 97.80 % of the essential oil were identified. The main chemical components revealed the presence of linalool, eugenol, eucalyptol, hinesol, trans-α-bergamotene and γ-cadinene as the major constituents. In conclusion, the essential oil extracted from greenhouse cultivated Ocimum basilicum European chemotype showed potent antitumor activity.

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Available abstract

In the current study, the compositions of the essential oil obtained from leaves of Ocimum basilicum ‘Cinnamon’ grown in Jordan in a greenhouse was analysed. The antitumor activity of the essential oil was examined against three different cancer cell lines including MDA-MB-231, MCF7 and U-87 MG. The hydrodistillation method was used to extract the essential oil from Ocimum basilicum and the chemical components were analyzed and identified using gas chromatography-mass spectroscopy. The dry weight yield of essential oil was 0.50 % (w/w). Thirty-one components representing 97.80 % of the essential oil were identified. The main chemical components revealed the presence of linalool, eugenol, eucalyptol, hinesol, trans-α-bergamotene and γ-cadinene as the major constituents. In conclusion, the essential oil extracted from greenhouse cultivated Ocimum basilicum European chemotype showed potent antitumor activity.

Key concepts: Ocimum, Basilicum, Eugenol, Essential oil, Linalool, Eucalyptol, Chemistry, Methyl eugenol

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