New understanding of the low-dose radiation-induced hormesis

Dr. Liu Shuzheng as a well-known educator and radiobiologist has started to work on the physiological benefits of low-dose radiation since 1970s. His research on the distinct effects of low-dose radiation from those of high-dose radiation has nationally and internationally impacted radiobiology, medicine and oncology. Therefore, here we briefly review the research from his research team from early years to last two decades. Two important facts related to LDR biological effects are the hormesis and adaptive response, both have been the main focuses of Dr. Liu Shuzheng early research. In the last couple of decades Dr. Liu Shuzheng have further investigated how to apply these important mechanisms into clinical translational research, such as the potential to application of LDR-hormesis to enhance tumor’s chemo- or radio-therapy and LDR-induced adaptive response to protect normal tissue from chemo- or radio-therapy related side toxic effects. Therefore, Dr. Liu has provided important guidance and role model for his trainees in the continue of their research career in radiation biology, medicine and oncology.