A study on comparison between recovery pattern after total intravenous anaesthesia using thiopentone sodium, ketamine hydrochloride and propofol for short surgical cases

Aim & Objectives: The aim of the present study is to compare the recovery pattern after total intravenous anaesthesia using thiopentone sodium, ketamine hydrochloride and propofol for short surgical cases. Methodology: The randomized controlled trial was a comparison between three groups of adult patients each receiving thiopentone sodium, ketamine hydrochloride or propofol as the anaesthetic agent. Analysis of variance (ANNOVA) was applied to all the variables. Barring four parameters the tests of homogeneity were round to be significantly different for the three drugs respectively. Hence it was decided to go for non-parametric tests.Results: In the present study, recovery of consciousness, cognitive and fine motor functions with thiopentone sodium was slower than with propofol but earlier than with ketamine hydrochloride. Recovery of cognitive and motor functions was slowest with ketamine hydrochloride. Recovery of gross motor activities like sitting, standing and walking was earliest with propofol and equivocal between thiopentone sodium and ketamine hydrochloride. Conclusion: Thus, propofol has the best recovery profile when compared with thiopentone sodium and ketamine hydrochloride for short surgical cases.