2009•Unpublished venueRequires access

Cytochrome P450 3A4 Enhances UDP-Glucuronosyltransferase 1A9-catalyzed Glucuronidation of SN-38, an Active Metabolite of Irinotecan

Yuji Ishii, Yuki Iwamoto, Toshiya Oizaki, Arief Nurrochmad, Yoshio Nishimura, Shinichi Ikushiro, Futoshi Taura, Satoshi Morimoto, Kiyoshi Nagata, Yasushi Yamazoe, Peter I. Mackenzie, Hideyuki Yamada

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Key concepts: Glucuronidation, Metabolite, Glucuronosyltransferase, Chemistry, Irinotecan, Active metabolite, Pharmacology, Catalysis

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Cytochrome P450 3A4 Enhances UDP-Glucuronosyltransferase 1A9-catalyzed Glucuronidation of SN-38, an Active Metabolite of Irinotecan — Research Paper | ScholarLens