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1988•Bulletin of Pharmaceutical Sciences AssiutOpen access

QUANTITATIVE MOLAR ABSORPTIVITY-STRUCTURE RELATIONSHIPS OF CERTAIN CATECHOLAMINES

Adel Youssef, Michael E. El‐Kommos, Hassan H. Farag

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Abstract

Molar absorptivities of six catecholamines (CA) are determined from their reactions with hydrochloric acid, boric acid molybdic acid, germanium dioxide, iron (II)-citrate and zirconyl chloride. Significant linear correlations are obtained between emax and the number of ligands. emax of most of the (CA) investigated shows a significant correlation with the molecular connectivity indices of the side chains and pka values. A dimeric state is suggested for (CA) in 0.1 N hydrochloric acid medium.

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Molar absorptivities of six catecholamines (CA) are determined from their reactions with hydrochloric acid, boric acid molybdic acid, germanium dioxide, iron (II)-citrate and zirconyl chloride. Significant linear correlations are obtained between emax and the number of ligands. emax of most of the (CA) investigated shows a significant correlation with the molecular connectivity indices of the side chains and pka values. A dimeric state is suggested for (CA) in 0.1 N hydrochloric acid medium.

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Available abstract

Molar absorptivities of six catecholamines (CA) are determined from their reactions with hydrochloric acid, boric acid molybdic acid, germanium dioxide, iron (II)-citrate and zirconyl chloride. Significant linear correlations are obtained between emax and the number of ligands. emax of most of the (CA) investigated shows a significant correlation with the molecular connectivity indices of the side chains and pka values. A dimeric state is suggested for (CA) in 0.1 N hydrochloric acid medium.

Key concepts: Molar absorptivity, Molar, Chemistry, Molar ratio, Biology, Paleontology, Optics, Biochemistry

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