Atractylodesin III maintains mitochondrial function and inhibits caspase-3 activity to reverse apoptosis of cardiomyocytes in AMI rats.
Mingying Cao, Cheng Yu, Zhuhua Yao, Xuemei Gao, Shu-Xing Wu
Abstract
Mingying Cao, Cheng Yu, Zhuhua Yao, Xuemei Gao, Shu-Xing Wu
Abstract
) compared to MG. Atractylodesin III decreased apoptosis of myocardial cells in AMI, up-regulated Bcl-2 expression, and inhibited Bax and Caspase-3 activity.
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) compared to MG. Atractylodesin III decreased apoptosis of myocardial cells in AMI, up-regulated Bcl-2 expression, and inhibited Bax and Caspase-3 activity.
Key concepts: TUNEL assay, Apoptosis, Terminal deoxynucleotidyl transferase, Western blot, Andrology, Saline, Caspase 3, Staining