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[Blood Test Patterns for Blood Donors after Nucleic Acid Detection in the Blood Center].

Shou-Shan Men, Lian-Zhi Lv, Yuanfeng Chen, Chunhua Han, Hongyu Liu, Yan Yan

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Abstract

OBJECTIVE: To investigate the blood test patterns for blood donors after nucleic acid detection in blood center. METHODS: persons the serological test yet should be performed. RESULTS: (91.66% of OBI), 5 might be HBV "window period" infective, moreover the HCV RNA and HIV RNA positive samples were not found. CONCLUSION: To avoid the missdiagnosis of donors with low level of virus, the nucleic acid test must be carried out after virus concentration of mixed samples when the blood test pattern of donors is nucleic acid test of mixed samples, otherwise the single nucleic acid test must be performed to obtain more high detected rate of virus nucleic acid. The HBcAb serologic test and physical examination of donors before blood donation must be enhanced on basis of serological test of HBsAg; for high risk people, the persuading no blood donation is simplest pattern.

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What this paper is about

OBJECTIVE: To investigate the blood test patterns for blood donors after nucleic acid detection in blood center. METHODS: persons the serological test yet should be performed. RESULTS: (91.66% of OBI), 5 might be HBV "window period" infective, moreover the HCV RNA and HIV RNA positive samples were not found. CONCLUSION: To avoid the missdiagnosis of donors with low level of virus, the nucleic acid test must be carried out after virus concentration of mixed samples when the blood test pattern of donors is nucleic acid test of mixed samples, otherwise the single nucleic acid test must be performed to obtain more high detected rate of virus nucleic acid. The HBcAb serologic test and physical examination of donors before blood donation must be enhanced on basis of serological test of HBsAg; for high risk people, the persuading no blood donation is simplest pattern.

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Available abstract

OBJECTIVE: To investigate the blood test patterns for blood donors after nucleic acid detection in blood center. METHODS: persons the serological test yet should be performed. RESULTS: (91.66% of OBI), 5 might be HBV "window period" infective, moreover the HCV RNA and HIV RNA positive samples were not found. CONCLUSION: To avoid the missdiagnosis of donors with low level of virus, the nucleic acid test must be carried out after virus concentration of mixed samples when the blood test pattern of donors is nucleic acid test of mixed samples, otherwise the single nucleic acid test must be performed to obtain more high detected rate of virus nucleic acid. The HBcAb serologic test and physical examination of donors before blood donation must be enhanced on basis of serological test of HBsAg; for high risk people, the persuading no blood donation is simplest pattern.

Key concepts: Nucleic acid, Nucleic acid test, Chromatography, Chemistry, Virology, Biology, Biochemistry, Medicine

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