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2017•PubMedRequires access

[Effect and related mechanism of miRNA-21 on hydrogen peroxide-induced C-kit(+) cardiac stem cells apoptosis].

Ranzun Zhao, Y Wang, Weijie Deng, B Shi, Xilin Long, Z L Wang, W M Chen

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Abstract

Overexpression of miRNA-21 protects the C-kit(+) cardiac stem cells from apoptosis caused by oxidative stress through downregulating proapoptotic and upregulating the antiapoptotic proteins.

About this research paper

What this paper is about

Overexpression of miRNA-21 protects the C-kit(+) cardiac stem cells from apoptosis caused by oxidative stress through downregulating proapoptotic and upregulating the antiapoptotic proteins.

Why it matters

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Method / approach

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Main findings

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Available abstract

Overexpression of miRNA-21 protects the C-kit(+) cardiac stem cells from apoptosis caused by oxidative stress through downregulating proapoptotic and upregulating the antiapoptotic proteins.

Key concepts: Annexin, Apoptosis, Transfection, Molecular biology, Western blot, microRNA, Messenger RNA, Pi

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[Effect and related mechanism of miRNA-21 on hydrogen peroxide-induced C-kit(+) cardiac stem cells apoptosis]. — Research Paper | ScholarLens