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2020•Drug Metabolism and DispositionOpen access

Critical Impact of Drug-Drug Interactions via Intestinal CYP3A in the Risk Assessment of Weak Perpetrators Using Physiologically Based Pharmacokinetic Models

Makiko Yamada, Shinichi Inoue, Daisuke Sugiyama, Yumi Nishiya, Tomoko Ishizuka, Akiko Watanabe, Kengo Watanabe, Shinji Yamashita, Nobuaki Watanabe

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Key concepts: Pharmacokinetics, Drug, Pharmacology, CYP3A, Drug metabolism, Physiologically based pharmacokinetic modelling, Medicine, Internal medicine

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Critical Impact of Drug-Drug Interactions via Intestinal CYP3A in the Risk Assessment of Weak Perpetrators Using Physiologically Based Pharmacokinetic Models — Research Paper | ScholarLens