Inhibition of neutrophil elastase prevents neutrophil extracellular trap formation and rescues mice from endotoxic shock
Emeka B. Okeke, Cameron Louttit, Chris Fry, Alireza Hassani Najafabadi, Kai Han, Jean A. Nemzek, James J. Moon
Abstract
Emeka B. Okeke, Cameron Louttit, Chris Fry, Alireza Hassani Najafabadi, Kai Han, Jean A. Nemzek, James J. Moon
Abstract
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Key concepts: Neutrophil extracellular traps, Neutrophil elastase, Proinflammatory cytokine, Elastase, In vivo, Proteases, Extracellular, Serine protease