2020New Journal of ChemistryRequires access

The first zwitterionic cocrystal of indomethacin with amino acid showing optimized physicochemical properties as well as accelerated absorption and slowed elimination in vivo

Ling‐Yang Wang, Yue‐Ming Yu, Fubin Jiang, Yan‐Tuan Li, Zhi‐Yong Wu, Cui‐Wei Yan

Open publisher page 33 citations

Abstract

The first zwitterionic cocrystal of indomethacin (INC) with proline (PL) with optimized in vitro / in vivo properties was prepared and characterized.

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The first zwitterionic cocrystal of indomethacin (INC) with proline (PL) with optimized in vitro / in vivo properties was prepared and characterized.

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OpenAlex reports 33 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

The first zwitterionic cocrystal of indomethacin (INC) with proline (PL) with optimized in vitro / in vivo properties was prepared and characterized.

Key concepts: Cocrystal, Chemistry, In vivo, Absorption (acoustics), Stereochemistry, Nuclear chemistry, Organic chemistry, Molecule

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The first zwitterionic cocrystal of indomethacin with amino acid showing optimized physicochemical properties as well as accelerated absorption and slowed elimination in vivo — Research Paper | ScholarLens